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The coffee plant of the family Rubiaceae consists over 90 flowering species of shrubs or small trees native to subtropical Asia and Africa. Coffee plant is cultivated and harvested on a very large scale due to the use of its seed or “bean”. The well know beverage, coffee, has made coffee bean the most widely traded agricultural commodity in the world. Coffee is a well known beverage in nearly every region of the globe. What is not well known are the many benefits of coffee consumption. Scientific studies have indicated that coffee may play a preventative role in some degenerative diseases including type II diabetes (1-2). The anti-oxidant properties of coffee have been shown to be significant with regular consumption (3). Further study has also implied that the constituents of coffee may also have some effect on glucose levels in the blood (4) as well as fat accumulation, and body fat maintenance in rodent models (5). There is evidence that the components of coffee bean, and in particular Green Coffee Bean act synergistically to benefit metabolic function and fat accumulation.
A recent study has indicated that green coffee bean has an inhibitory effect on fat accumulation and body weight gain in rodents (5). The principle constituents of green coffee bean were found to be chlorogenic acid and caffeine. After two weeks of oral administration of green coffee bean extract, there was a marked decrease in visceral fat accumulation and weight gain in those rats fed rats fed green coffee bean extract compared to rats fed normally, or those given caffeine and chlorogenic acid separately. Chlorogenic acid alone, however, was found to reduce liver triglycerides. Even when triglyceride levels were intentionally elevated with a high fat diet, green coffee bean extract exhibited a lowering effect in serum fat levels. According to this study the potency of the extract is dependent upon the presence of both chlorogenic acid and caffeine (5).
Excluding any synergistic effects, chlorogenic acid was found to selectively inhibit the glucose-6-phosphatase, an essential enzyme in the production of glucose in the liver (4). This activity is indicative of significant blood glucose control. Compounded with the hypotensive effects seen in hypertensive animal models (6), green coffee bean has serious implications for the maintenance of some of the most prominent diseases in modern society. This claim is even further supported by it anti-oxidant capability. HerbaKraft Green Coffee Bean Extract has been found to have and ORAC value greater than 6500 µmoleTE/g. Our Green Coffee Bean extract has a higher concentration of chlorogenic acid than the standards used in the previous studies. In addition synergistic effects are still present due to the concentrated caffeine content ranging from 3-5%. It is clear that Green Coffee Bean has numerous significant effects on the body. HerbKarft offers excellent quality Green Coffee Bean Extract standardized to 50% chlorgenic acid and caffeine. Its antioxidant capability and implications in degenerative disease treatments suggest that this material has serious medical application. There is no doubt that Green Coffee Bean Extract is a vastly beneficial material. Its incorporation into daily supplements and foods would certainly provide an advantage for any person concerned with the health risks of the modern world.
References
1. Van Dam R, Feskens E. Coffee consumption and risk of type 2 diabetes mellitus. Lancet 2002, 360: 1477-1478.
2. Freedholm BB, Lindgren E. the effect of alkylxanthines and other phospodiesterase inhibitors on adenosine-receptor mediated decrease in lipolysis and cyclic AMP accumulation in rat fat cells. Acta Pharmacol Toxico 1984, 54:64-71.
3. Richelle M, Tavazzi I, Offord E. Comparison of the Antioxidant Activity of Commonly Consumed Polyphenolic Beverages (Coffee, Cocoa, and Tea) Prepared per Cup Serving. J. Agric. Food Chem., 2001, 49 (7), pp 3438–3442
4. Arion WJ, Canfield W, Ramos F, Schindler P, Burger H, Hemmerle H, Schubert G, Below P, Herling A. Chlorogenic acid and hydroxynitrobenzaldehyde: new inhibitors of hepatic glucose-6-phosphate. Arch Biochem Biophys 1997, 339:315-322.
5. Shimoda H, Seki E, Aitani M. Inhibitory effect of green coffee bean extract on fat accumulation and body weight gain in mice. BMC Complementary and Alternative Medicine 2006 6:9 -18
6. Suzuki A, Kagawa D, Ochiai R, Tokimitsu R,Saito I. Green coffee bean extract and its metabolites have a hypotensive effect in spontaneously hypertensive rats. Hypertens res 2002 25: 99-107.
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