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Ashwagandha
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Ashwagandha (Withania Somnifera) is a pl..........
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Garcinia
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Garcinia cambogia, commonly known as ..........
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Vitafoods
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May 18-20, 2010
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GENEVA PALEXPO
SWITZERLAND
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Guggul
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Guggul is the resin collected from the Commiphora Mukul tree. Also known as the myrrh tree, Commiphora mukul, is a small thorny plant native to India. The yellowish brown resin has been used historically for medicinal reasons and serves as the source of guggul. Traditionally this substance has been connected to high triglyceride levels, acne vulgaris, atherosclerosis, high cholesterol, osteoarthritis and obesity. In recent years there have been several studies that evaluated the true benefits of guggul with promising results. Guggul's constituents include resin, volatile oils, and gum. It's active and most influential compound would be ketonic steroid compounds known as guggulsterones. These compounds have shown to have triglyceride and cholesterol lowering capabilities and even some anti-cancer effects. Guggul has also shown to promote blood and heart health through a number of other mechanisms as well.
The activities of guggulsterones are quite striking. Historically guggul was not associated with cancer however, one recent study demonstrated that they it in fact contains some anti-leukemic effects. The results of the study showed that guggulsterones and its isomers inhibited leukemic cell proliferation and induced apoptosis (Samudio, 2005). Guggulsterones have also proved to inhibit cholesterol synthesis by inhibiting the farsenoid X receptor and the bile-acid receptor in the liver (Singh, 1994). Several studies done in India have actually shown quite significant benefits of guggul extract supplementation. It has shown to decrease total cholesterol, triglycerides, and LDL levels (bad cholesterol) while increasing HDL (good cholesterol) levels (Agarwal, 1986) (Gopal, 1986) (Malhorta, 1977) (Verma 1988) (Nityanand, 1989) (Kappurajan, 1978). Lowering cholesterol and triglyceride levels helps to inhibit atherosclerosis and promotes overall heart health. A daily dose of guggul is truly beneficial to the health conscious consumer. |
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References
Agarwal RC, Singh SP, Saran SK et al. Clinical trial of gugulipid-a new hypolipidemic agent of plant origin in primary hyperlipidemia. Indian J Med Res. 1986; 84:626-32.
Gopal K, Saran RK, Nityanand S et al. Clinical trial of ethyl acetate extract of gum gugulu (gugulipid) in primary hyperlipidemia. J Assoc Physicians India. 1986; 34:249-51.
Malhotra SC, Ahuja MMS, Sundaram KR. Long term clinical studies on the hypolipidaemic effect of Commiphora mukul (guggulu) and clofibrate. Indian J Med Res. 1977; 65:390-5.
Nityanand S, Srivastava JS, Asthana OP. Clinical trials with gugulipid, a new hypolipidaemic agent. J Assoc Physicians India. 1989; 37:323-8.
Verma SK, Bordia A. Effect of Commiphora mukul (gum guggulu) in patients of hyperlipidemia with special reference to HDL-cholesterol. Indian J Med Res. 1988; 87:356-60.
Kuppurajan K, Rajagopalan SS, Koteswara Rao T et al. Effect of guggulu (Commiphora mukul-Engl.) on serum lipids in obese, hypercholesterolemic and hyperlipemic cases. J Assoc Physicians India. 1978; 26:367-73.
Samudio K, Konopleva M, Safe S, McQueen T, Andreef M. Guggilsterones induce apoptosis and differentiation in acute myeloid leukemia: identification of isomer-specific antileukemic activities of the pregnadienedione structure. Mol Cancre Ther. 2005 4(12):1982-1992.
Singh RB, Niaz MA, Ghosh S. Hypolipidemic and antioxidant effects of Commiphora mukul as an adjunct to dietary therapy in patients with hypercholesterolemia. Cardiovasc Drugs Ther. 1994; 8:659-64. |
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Disclaimer: The statements here in have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent disease. |
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HerbaKraft Organics
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HerbaKraft now offers an extensive line of certified organic materials. In our efforts to benefit the well-being of the environment and the consumer, we now offer materials that are organically cultivated, collected and produced in accordance with USDA and NOP certification standards.
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Products: Latin Name/ Common Name |
Actives |
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ANDROGRAPHIS PANICULATA (KALMEGH) |
ANDROGRAPHOLIDES (HPLC) |
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ASPARAGUS RACEMOSUS (SHATAVRI) |
SAPONINS |
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AZADIRACHTA INDICA (NEEM) |
BITTERS |
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BACOPA MONNIERI (NIR-BRAHMI) |
SAPONINS
BACCOSIDES
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BOSWELLIA SERRATA (SALAI GUGGAL) |
BOSWELLIC ACID |
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CASSIA ANGUSTIFOLIA (SENNA) |
SENNOSIDES |
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CENTELLA ASIATICA (MANDUKPARNI) |
TOTAL TRITERPENES
ASIATICOSIDES (HPLC) |
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COLEUS FORSKHOLII ROOT |
FORSKHOLIN (HPLC) |
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COMMIPHORA MUKUL (GUGGAL) |
TOTAL GUGGAL STERONES
E&Z GUGGAL STERONES HPLC |
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COMMIPHORAL MUKUL (GUGGAL PURIFIED) |
TOTAL GUGGAL STERONES |
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ECLIPTA ALBA (BHRINGRAJ) |
WADELOLACTONES |
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EMBLICA OFFICINALIS (AMLA) |
TANNINS |
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GARCANIA CAMBOGIA |
(-) HYDROXYCITRIC ACID (HPLC) |
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GARCINIA EXTRACT (WATER SOLUBLE) |
(-) HYDROXYCITRIC ACID (HPLC) |
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GINGER |
GINGEROLS |
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GYMNEMA SYLVESTRE (GURMAR) |
GYMNEMIC ACID |
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LAGERSTROEMIA SPECIOSA (BANABA) |
CROSOLIC ACID |
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MOMORDICA CHARANTIA (Bitter melon) |
BITTER |
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MORINDA CITRIFOLIA FRUIT (NONI) |
ALKALOIDS
XERONIN |
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MUCUNA PRURIENS (KAUNCH) |
LEVO DOPA |
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NARDOSYTACHYS GRANDIFLORA (JATAMANSI) |
JATAMANSIC ACID |
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OCIMUM AMERICANUM (Lemon Basil) |
TANNINS |
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(TULSI/HOLY BASIL) |
URSOLIC ACID |
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PICRORRHIZA KURROA (KUTKI) |
BITTER
KUTKIN (HPLC) |
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PHYLLANTHUS AMARUS HERB (BHUMI AMLA) |
BITTER |
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SYLIBUM MARIANUM (Milk Thistle) |
Sylimarin |
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TERMINALIA CHEBULA FRUIT (HARITAKI) |
TANNINS |
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TERMINALIA BELLERICA FRUIT (BAHEDA) |
TANNINS |
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TRIPHALA (MIXTURE OF THREE MYROBALANS) |
TANNINS |
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TRIFOLIUM ALEXANDRIANUM (CLOVER) |
PROTEINS |
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TRIBULUS TERRESTRIS FRUIT (GOKHARU) |
SAPONINS
PROTODIOSCIN (HPLC) |
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VALERIAN WALLICHII ROOT (TAGAR) |
VALERIC ACID |
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WITHANIA SOMNIFERA ROOT (ASHWAGANDHA) |
ALKALOIDS
WITHANOLIDES |
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Boswellia Serrata 65
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Boswellia serrata also known as Frankincense has been used for centuries for a number of ailments. More recently its therapeutic application to inflammatory diseases has made it a notable ingredient. Skepticism may be laid to rest due to a recent review of the clinical efficacy of Boswellia performed by Ernst (2008). Several clinical studies of approved methodological quality showed the clinical effectiveness of Boswellia serrata in relation to asthma, arthritis, Crohn’s disease, and colitis. The active component of Boswellia, boswellic acid, is thought to inhibit the production of leukotrienes, the necessary molecules needed for inflammation to occur. According to Ammon (2002) this inhibition occurs due to the binding of Boswellic acids to the enzyme 5-lipoxygenase. The binding of this enzyme, interrupts its activity, rendering it incapable of participating in leukotriene biosynthesis. As an anti-inflammatory, Boswellia serrata is certainly a capable and effective aid.
References
Kimmatkar, N. Efficacy and tolerability of extract in treatment of osteoarthritis of knee: A randomized double blind placebo controlled trial. Phytomedicine. 2003. 10 (1): Page 3
Gupta I, Parihar A, Malhotra P, Gupta S, Ludtke R, Safayhi H, Ammon HP. Effects of gum resin of Boswellia serrata in patients with chronic colitis. Planta Med 2001 Jul;67(5):391-5
Ernst. E. Frankincense: systematic review.BMJ. 2008 Dec 17;337:a2813. doi: 10.1136/bmj.a2813.
Ammon HP. [Boswellic acids (components of frankincense) as the active principle in treatment of chronic inflammatory diseases]. Wien Med Wochenschr. 2002;152(15-16):373-8.
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Guggul
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Guggul is the resin collected from the C....
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